Leymus Genomics and Loop Genomics at ESHG 2019 in Gothenburg

Leymus Genomics and Loop Genomics were at ESHG 2019

Thanks again to all the wonderful people who visited us at this year’s European Society of Human Genetics (ESHG) conference in Gothenburg. We were overwhelmed by all the positive feedback Leymus Genomics had with Loop Genomics’ stand, and we enjoyed talking to all of you. Indira Wu, Loop’s Director of Molecular Biology, had a sold-out presentation at ESHG on the principles and applications of the LoopSeq kits. If you missed it, or would like to hear it again, please see the video below or you can download the slide deck. The last 10 minutes is a very exciting Q&A – we know it’s mind-blowing (!) that you can actually do long-read sequencing on an Illumina sequencer. ESHG said they’d never seen such a turnout for a first-time presenter at a satellite meeting!

 

Slide deck: Loop Genomics ESHG slide deck

 

Loop Genomics has developed a synthetic long-read sequencing technology that leverages existing Illumina® short read sequencers coupled with LoopSeq® barcoding technology to enable single-molecule, long-read sequencing on any Illumina® infrastructure. The benefits include: 

  • Synthetic long-read NGS kit
  • Uses your existing Illumina sequencer – no extra instruments
  • Multiplex single-tube workflow
  • Consensus error correction – error rates reduced 40x vs short reads
  • Full isoform mapping for transcriptome research
  • True quantitative results due to transcript counting using UMIs and full-length reads
  • Better resolution on species and strain level for microbiome research

You can learn more here: https://www.loopgenomics.com/learn

 

Leymus Genomics is the distributor of the LoopSeq kits in northern Europe, so please get in contact with us if you feel you or your company could benefit from getting long-read data from your Illumina short-read sequencers with just a kit including free and intuitive software  – no additional hardware.


New hire at Leymus Genomics! Please welcome Kristine Kjær, who will be joining the team as the scientific sales and training contact responsible for Loop Genomics. Kristine has a MSc in Molecular Biology and will be supporting our customers in how to get the best possible data from the LoopSeq kits. With the right support our customers can get the full benefits of producing high quality long-read data on your existing Illumina short-read sequencers. LoopSeq allows you to:

  • do single-molecule counting
  • multiplex your workflow
  • the kits include a full report + long-read FASTQ file

If you need more information about how Loop can help your research, need training in how to use the kits, or want to chat about how the technology works, just contact us.

We invite you to hear the talk by Loop Genomic's Indira Wu at ESHG 2019

Hear the talk by Loop Genomic's Indira Wu at ESHG on Monday, June 17, 15:00 - 16:30 in Room A-4.

  • Synthetic long-read NGS kit
  • Uses your existing Illumina sequencer – no extra instruments
  • Multiplex single-tube workflow
  • Consensus error correction - error rates reduced 40x vs short reads
  • Full isoform mapping for transcriptome research
  • True quantitative results due to transcript counting using UMIs and full-
    length reads
  • Better resolution on species and strain level for microbiome research

Loop Genomics has developed a synthetic long-read sequencing technology
that leverages existing Illumina® short read sequencers coupled with LoopSeq®
barcoding technology to enable single-molecule, long-read sequencing on any
Illumina® infrastructure.

Indira Wu, the Director of Molecular Biology at Loop Genomics, will in her talk
explore LoopSeq® sequencing technology and how it provides previously
inaccessible layers of information from Illumina®-generates sequences,
enabling a wide variety of diverse sequencing application, including sequencing
of microbiomes, transcriptomes, targeted amplicons, and more.


DDN awards Leymus Genomics the prestigious partnership prize

DDN awards Leymus Genomics the prestigious partnership prize

Berlin, 11th of April 2019

We are looking forward to continuing the collaboration on installing the best data storage at scale for genomics, life sciences, and AI.

Leymus Genomics works to create value for genomic sites that need data storage with highly reliable performance and also the best priced data storage as demonstrated recently at the data storage project at SciLifeLab Clinical Genomics Stockholm.


Full length 16S Sequencing with short reads: Simpler, better & cost-effective

Full-length 16S Sequencing with short reads: Simpler, better & cost-effective

Leveraging your existing sequencing infrastructure, Loop Genomics improves the accuracy of 16S sequencing with our LoopSeqTM Complete and LoopSeqTM Select products.

With LoopSeq Complete and LoopSeq Select you get:

Enhanced performance

  • „More comprehensive species identification „
  • More accurate species classification
  • More accurate relative species abundance

A cost-effective solution

  • „Uses your existing short-read sequencing infrastructure „
  • Requires no additional hardware
  • Saves time and labor with a simple, streamlined workflow

Powerful technology

  • „  Converts your existing short-read sequencer into a long-read, single-molecule counting instrument
  • „  Smartly implements a synthetic long-read approach
  • „  Increases sequencing accuracy (error rate <0.005%)

 

Discounted test kit

Available on request, or alternatively test as a send out of your samples.

Learn more

https://www.loopgenomics.com/learn


Leymus Genomics partners with NVIDIA with focus on AI & WGS data analysis

Leymus Genomics partners with NVIDIA with focus on AI & WGS data analysis

Bioinformatics for whole genome sequencing data.

Leymus Genomics is excited to start collaborating with NVDIA. Our focus is on whole-genome sequencing data and associated health data.

You might be familiar with NVIDIA’s GEFORCE graphic cards for computer games – NVIDIA is developing GPUs for most of the computers and scientists in the world working with AI and parallel computing.

Sequencing analyses of whole human genes benefit by using NVIDIA CUDA-enabled GPUs. There is now progress on using GPUs for a range of bioinformatics and life sciences codes.

Leymus Genomics supports and collaborates with Parabricks WGS secondary analysis program for the GATK pipeline running on CUDA cores from NVIDIA. With Parabricks you can expect to speed up your analysis time with 30-50x*. We would like to talk to you if you are about to analyze >100 human genomes and you can see speed and data infrastructure as potential issues.

* This depends on the data infrastructure and number of CPUs at the genomic site.


Leymus Genomics onboards new data scientists

Leymus Genomics onboards new data scientists

Leymus Genomics is very happy to welcome our two new data scientists and partners, Niels Buus Lassen and René Madsen, to our team. This will further our goals of providing world leading data solutions for medium to very large scale genomic labs. Niels and René bring a combined 30 years of working with complex statistical modeling, machine learning, AI, deep learning and developing enterprise software to the company. The addition to the team will open up opportunities for Leymus Genomics to work with data intensive challenges in the genomics field. We are interested in further partnerships in the development of better models for analysing large data sets of genomic data. Leymus Genomics can today provide the full workflow from on-site data storage (DDN), GPUs to accelerate your analysis (official announcement on Monday Oct 8th), WGS secondary analysis on GPUs (Parabricks), and AI consulting and development.


New Partnership with Parabricks

New Partnership with Parabricks

High Performance Secondary Analysis of Genomic Data

Leymus Genomics are happy to announce our partnership with Parabricks, the first to bring secondary analysis with GATK to GPUs in the cloud or local with NVIDIA.

Parabricks provides 30-50 times faster secondary analysis of FASTQ files coming out of sequencers to VCF files that have the variants for tertiary analysis. Parabricks accelerates existing GATK best practices to generate equivalent results as the baseline CPU-only solution.

  • Turnkey Solution: Parabricks software runs on standard CPU and GPU nodes available on the cloud and requires no additional setup steps by the user.
  • On-Premise and Cloud Agnostic: The Parabricks software can run on local servers like DGX-1 servers or public cloud such as AWS, Google Cloud Services and Microsoft Azure.
  • 100% Deterministic and Reproducible: Any configuration of Parabricks software on any platform with any number of resources, generates the exact same results every execution.
  • Equivalent results: Parabricks’ pipeline generates equivalent results as baseline GATK 4 best practices pipeline as the same algorithm is used.

 

Website

https://www.parabricks.com/


NGS Service lab for Scandinavian researchers

We are happy to celebrate our 1 year anniversary since going live at ESHG on the 27th of May in Copenhagen in 2017. To celebrate this we will have a NGS/Microarray service lab campaign from the 1st of May to the 30th of June.

RNA Seq*
249 € per sample

Illumina EPIC 850K Methylation Array**
315 € per sample

RNA Seq + Illumina EPIC 850K Methylation Array***
559 € per sample

Exome Seq****
399 € per sample

* 15 Mill reads min of 48 samples

** Min of 96 samples, High quality samples. If FFPE samples there will be an add-on fee.

*** Min 48 samples 15 Mill reads per sample for RNA seq

 **** Min 96 samples, 16 million reads

This is a time-limited campaign which expires August 31stst, 2018

GenomeScan one of the first NGS service labs in the world – a leader in Genomic analysis – from sample to analysis:

  • GLP and ISO/IEC 17025 (L518) accredited
  • NGS platforms includes HiSeq 4000, HiSeq 2500, Nextseq 500, PacBio, 10x (Chromium platform)
  • Transcriptomics, Epigenetics, Single cell seq., WGS, WES
  • From sample to bioinformatics analysis
  • R&D facility provides the most cutting-edge techniques
  • Industry leading turnaround time
  • Leymus Genomics will be your local partner in discussing the right approach for your next NGS project. We provide full NGS service for the Nordic countries in collaboration with GenomeScan


Leymus Genomics went live at ESHG 2017

Thank you for all the interesting discussions at ESHG. Pictures from Leymus at ESHG, International High Performance Computing in Frankfurt, and DSKB 2017 (Danish Society for Clinical Biochemistry). We learned that several of our solutions around the NGS workflow – e.g. DDN Data storage and BioDynami NGS library prep – are faster and more simple than existing solutions. We look forward to seeing you in your lab.