Magnetic Beads (NGS Clean Up)
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Magnetic Beads (NGS Clean Up)
- DNA and RNA clean-up for next generation sequencing library construction
Manufacturer: CleanNA
The CleanNGS kit offers a highly efficient magnetic bead based clean-up system for the purification of both DNA and/or RNA for next-generation sequencing and sanger sequencing workflows. It can also be used for CRISPR-Cas9. CleanNGS provides maximum flexibility allowing for left, right or double-sided size selection by easily adjusting the sample to CleanNGS volume ratio(s).
Based on CleanNA’s proprietary chemistry CleanNGS removes, salts, primers, primer-dimers and dNTPs, while DNA and/or RNA fragments are selectively bound to the magnetic particles based on their size. Purified DNA and RNA is eluted of the magnetic particles using water or a low salt buffer and can be used directly for downstream applications such. The protocol can be adapted to your current liquid handling workstation (e.g. Hamilton, Beckman, Agilent, Caliper, Perkin Elmer, Tecan and Eppendorf) utilizing your current protocol as well as being used manually.
Amplicons purified with CleanNGS system are ready to be used in the following applications:
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- Next-Generation Sequencing
- PCR
- Genomic DNA clean up
- RNA clean up
- Fragment Analysis
- Microarrays
- Restriction enzyme clean up
- Cloning
Learn more about our magnetic plates, such as the 96 Well Magnet Plates.
PAPERS
Jestin George, Tim Kahlke, Raffaela M. Abbriano, Unnikrishnan Kuzhiumparambil, Peter J. Ralph and Michele Fabris.
Anca Liliana Cismaru, Livia Grimm, Deborah Rudin, Luisa Ibañez, Evangelia Liakoni, Nicolas Bonadies, Reinhold Kreutz, Pär Hallberg, Mia Wadelius, EuDAC Collaborators, Manuel Haschke, Carlo R. Largiadèr and Ursula Amstutz.
Features
- Designed for both DNA and RNA purification
- Ideal for (double-sided) size selection for Next-Generation Sequencing
- Efficient removal of unincorporated dNTPs, primers, primer dimers and other contaminants
- No centrifugation or filtration
Reviews
“At DNASense we have shifted our NGS clean up to CleanNA beads, in our comparison tests they are performing as good as or better than other leading NGS Clean-up beads”
Mads Albertsen: Professor applied Bioinformatics, Aalborg University, Founding CEO DNASense
“Amazing results!
These beads are easy to use, and are extremely effective in our applications. The beads produce high quality results and also produce extremely reproducible work. My research would not be the same without these cost-effective and efficient beads. I also appreciate how friendly and the willingness to help that all of the sales team has at GC Biotech to help provide me with what I want.”
Michelle Michelsen, University of Exeter